experience of disseminated intravascular coagulation [DIC] at periphery of Karachi

The purpose of this study is to describe the common causes and clinical presentations of Disseminated Intravascular Coagulation at periphery of Karachi. It was a descriptive study conducted by the department of Medicine at Jinnah Medical and Dental College Hospital, Korangi, from January 08 to December 08. Jinnah Medical and Dental College Hospital, provides health care facilities to the rural areas of Karachi including Sharafi, Chashma, Rehri Goths etc. We studied mode of presentation, laboratory investigation, treatment options and mortality. All the findings were recorded on a pre-designed Proforma. Sixty patients with Disseminated Intravascular Coagulation [DIC] were studied as protocol. Out of sixty cases 36 [60%] were male and 24 [40%] were female. Patients were 13-65 years of age mean 37.33%. Out of sixty patients 50 [83.3%] presented with bleeding and hemorrhage from various sites and only 10 [16.6%] presented with signs of hypercoagubility. Bacterial infection was found to be most common underline illness. The mortality rate was 43.3% in this study the mortality rate was higher in patients in which underlying illness was not easily curable. Disseminated Intravascular Coagulation [DIC] has various modes of presentation with very high mortality all over the world. In our study the majority of patients presented with bleeding from various sites, and the main causative agent was infective illness, so it is advisable if patient presented with bleeding and has history of infective illness than Disseminated Intravascular Coagulation [DIC] should be included in differential diagnosis

Coagulación intravascular diseminada, desencadenada por CEC. Diagnóstico tromboelastográfico (TEG). Reporte de caso / Intravascular diseminated coagulation secundary to ECC, thrombelastographic diagnosis (TEG). A case report

Cada día es más frecuente el uso de transfusión de productos sanguíneos y derivados en el transoperatorio, debido al creciente aumento de técnicas quirúrgicas más complejas asociadas a perdida importante de sangre (trasplante hepático, cirugía cardíaca, etc.). Sin embargo, el uso indebido de productos sanguíneos, no está excento de riesgos. Es por eso que desde mucho tiempo atrás, el monitoreo de la coagulación ha sido de vital importancia clínica, para el juicio correcto de la transfusión. Uno de los métodos que más auge está teniendo es el monitoreo de la coagulación mediante tromboelastografía (TEG). En el presente caso observamos la evolución tromboelastográfica de un paciente sometido a cambio valvular de la tricúspide y tromboendarterectomía de la aurícula derecha, antes, durante y después de la cirugía y que llevó finalmente el desarrollo de coagulación intravascular diseminada (CID) en el postoperatorio inmediato. Y se hace además una revisión de la literatura al respecto

Análise dos casos de choque séptico e coagulaçäo intravascular disseminada em UTI: pediatria / Septic shock and disseminated intravascular coagulation in the intensive care unit

Realizou-se uma análise retrospectiva de 44 internaçöes na UTI pediátrica da Universidade Estadual Paulista-Unesp por choque séptico e coagulaçäo intravascular disseminada (CIVD), diagnosticados de acordo com os critérios propostos por Sprung (1991) e história crônica e laboratorial compativel com CIVD, segundo os critérios descritos por Forbes (1990) e Montgomery e Hathaway (1980). No periodo estudado 27,5 por cento dos pacientes sépticos apresentaram choque séptico e CIVD, grupo de risco foram lactentes menores de 6 meses (mais ou menos 55 por cento), desnutridos de II e II grau (>60 por cento), associaçäo infecciosa e falência de múltiplos órgäos e sistemas de acordo com critérios propostos por Wilkinson (DMOS> 4 órgäos.=80 por cento mortalidade). Encontrou-se alteraçäo hematológica no grupo de óbitos e nos sobreviventes, porém com maior gravidade nos óbitos